
The Anal Cancer Information website is designed to provide patients and their doctors with some of the latest information on anal cancer, its likely precursor, anal intraepithelial neoplasia (AIN), and the virus that we believe to be responsible for AIN and anal cancer, human papillomavirus (HPV). HPV is also the cause of warts.
Anal cancer is a growing problem in the United States and many other developed countries. Like cancer of the cervix, it is caused by HPV. As you will learn by going to different links, HPV infection of the anal canal is surprisingly common. Anal HPV infection is most commonly acquired through anal intercourse, but it can also be acquired from other genital areas that are infected, particularly from the vulva in women, or from the penis in men. Fingers, toys, etc, can probably lead to anal HPV infection as well.
Research tells us that sexually active individuals, both men and women, may be at risk. The good news is that only a fraction of people with anal HPV infection will develop a lasting case of AIN, and even fewer will develop anal cancer. Men and women who are immunocompromised by human immunodeficiency virus (HIV) infection, organ transplant or other reasons are at especially high risk.
So who should be interested in this website?
- Men and women with a history of anal intercourse
- Men and women with a history of perianal (outside the anus) or vulvar warts
- Men and women who are immunocompromised, such as those who are HIV positive, or have received organ transplants

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